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Mrs. Saberhagen
Mrs. Saberhagen
is the mother of Salem and the grandmother of Annabelle. She only appears in the Season 2 episode "Mom vs. Magic," and dotes on her son even though he was worried that she would be cynical and overbearing upon discovering that he was sentenced to be a cat for 100 years. Unfortunately, she realized that she was now allergic to Salem and went under the knife to fix the problem.
Salem and his mom

She was allergic to Salem